Diuretics

Loop Diuretics (Furesemide, torsemide, bumetanide and Ethacrynic Acid) are the inhibitors of Na/K/2Cl cotransport system in thick ascending limb of loop of Henle.

Drugs in this category are:
furosemide
bumetanide
torsemide
ethacrynic acid

Loop diuretics inhibit the Na+/K+/2Cl− co-transporter channel in the ascending limb of the lop of henle.
Na+, Cl−, and K+ are lost in the urine

Used in Edema, Heart failure, Nephrotic syndrome

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