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Diuretics- Thiazide Diuretics.Pharmacology of Thiazide Diuretics

Thiazide diuretics (water pills) are medications that are used to treat highblood pressure (hypertension) and reduce fluid accumulation in the body. They work by reducing the ability of the kidneys to reabsorb salt and water from the urine and into the body thereby increasing the production and output of urine (diuresis).
The examples are chlorthalidone (Thalitone)

hydrochlorothiazide (Microzide)

methyclothiazide

Thiazide diuretics are used to treat high blood pressure and congestive heartfailure as well as the accumulation of fluid and swelling (edema) of the body caused by conditions such as heart failure,cirrhosis, chronic kidney failure,corticosteroid medications, and nephrotic syndrome.
Side effects of thiazide diuretics are dose related and include:

dizziness and lightheadedness,

blurred vision,

loss of appetite,

itching,

stomach upset,

headache, and

weakness.


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